(2E,6E,10E,14E,18E,22E,26E,30E)-1-Bromo-3,7,11,15,19,23,27,31,35-nonamethyl-2,6,10,14,18,22,26,30,34-hexatriacontanonaene → Phthalimide

A mixture comprising 17.4 g of solanesyl bromide, 5.6 g of potassium phthalimide and 70 ml of N,N-dimethylformamide was stirred for 2 hours, followed by stirring at 60° C. for an additional hour. Insoluble matters were separated by filtration, and the filtrate was concentrated under reduced pressure. The residue was dissolved in ethyl acetate, washed successively with water and saturated brine, dried over anhydrous sodium sulfate and then concentrated under reduced pressure. The residue was purified by means of silica gel chromatography (eluted with a mixture of n-hexane and benzene) to obtain 12,8 g of N-solanesyl phthalimide (yield, 67%, m.p., 51°-53° C.).

1. stirringby stirring at 60° C. for an additional hour
2. customInsoluble matters were separated by filtration
3. concentrationthe filtrate was concentrated under reduced pressure
4. dissolutionThe residue was dissolved in ethyl acetate
5. washwashed successively with water and saturated brine
6. dry with materialdried over anhydrous sodium sulfate
7. concentrationconcentrated under reduced pressure
8. customThe residue was purified by means of silica gel chromatography (
9. washeluted with a mixture of n-hexane and benzene)

ORDレコード

ord-ca9c9ed8b8834fa2bc5840adb39a66fe

出典データセット

uspto-grants-1981_05

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US04265910