Potassium Fluoride → 5-Fluoro-N-isopropylpyrimidin-2-amine
反応式
[CH:1]([NH:4][C:5]1[N:10]=[CH:9][C:8](Br)=[CH:7][N:6]=1)([CH3:3])[CH3:2].[F-:12].[K+]>>[CH:1]([NH:4][C:5]1[N:10]=[CH:9][C:8]([F:12])=[CH:7][N:6]=1)([CH3:3])[CH3:2]参加物
3
実験手順
Stoichiometric proportions of 2-isopropylamino-5-bromo-pyrimidine, prepared as described in example 1, and potassium fluoride were reacted together for 5 hours. After appropriate working up, the title compound was obtained as a white powder in a yield of 83%. Elemental analysis showed that the compound had the expected empirical formula of C7H10N3F.
後処理
- customwere reacted together for 5 hours
出典と根拠
- ORDレコード
- ord-81d3faac23584c64b4401be39246cbfa
- 出典データセット
- uspto-grants-1981_05
- 特許番号
- US04267181
反応ノート
読み込み中…