Triethylamine → HCID 23462554、化合物

HRID 2286760ノート

反応式

HRID 2286760 の反応式
[CH2:1]=[CH:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8].[CH3:10][CH:11]1[C:16](=[O:17])[CH2:15][CH2:14][CH2:13][C:12]1=[O:18].C(N(CC)CC)C>C(OCC)(=O)C>[CH3:10][C:11]1([CH2:1][CH2:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8])[C:16](=[O:17])[CH2:15][CH2:14][CH2:13][C:12]1=[O:18]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 709452-Methyl-1,3-cyclohexanedioneHCID 118047521,7-Octadien-3-one

生成物 1

HCID 23462554HCID 23462554、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

1,7-Octadien-3-one(0.24 g), 2-methyl-1,3-cyclohexanedione(0.5 g) and triethylamine (1 ml) are added to ethyl acetate (10 ml), and the mixture is stirred at room temperature for 24 hours. The triethylamine and acetic acid are evaporated off and the residue is purified by silica gel column chromatography(methylene chloride) to recover 0.39 g of the above-indicated compound. [IR 1700-1730 cm-1, 920 cm-1 ; NMR 1.10 ppm(3H, singlet, --CH3), 4.6-6.0 ppm(3H, multiplet, vinyl)].

後処理

  1. customThe triethylamine and acetic acid are evaporated off
  2. customthe residue is purified by silica gel column chromatography(methylene chloride)
  3. customto recover 0.39 g of the above-indicated compound

出典と根拠

ORDレコード
ord-4f38ba43deb04cac9a2e07775cec7896
出典データセット
uspto-grants-1981_05
特許番号
US04267377

反応ノート

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