Triethylamine → HCID 12944854、化合物

HRID 2286761ノート

反応式

HRID 2286761 の反応式
[CH2:1]=[CH:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8].[CH3:10][CH:11]1[C:15](=[O:16])[CH2:14][CH2:13][C:12]1=[O:17].C(N(CC)CC)C>C(OCC)(=O)C>[CH3:10][C:11]1([CH2:1][CH2:2][C:3](=[O:9])[CH2:4][CH2:5][CH2:6][CH:7]=[CH2:8])[C:15](=[O:16])[CH2:14][CH2:13][C:12]1=[O:17]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 130052-Methyl-1,3-cyclopentanedioneHCID 118047521,7-Octadien-3-one

生成物 1

HCID 12944854HCID 12944854、化合物

試薬・触媒・溶媒 1

HCID 8857Ethyl Acetate溶媒

実験手順

1,7-Octadien-3-one(1.782 g), 2-methyl-1,3-cyclopentanedione (2 g) and triethylamine (4 ml) are added to ethyl acetate (40 ml) and the mixture is stirred at room temperature for 30 hours. The triethylamine and ethyl acetate are evaporated off and the residue is purified by silica gel column chromatography (methylene chloride) to recover 2.744 g of the above-indicated compound. [IR 1723 cm-1, 1641 cm-1, 918 cm-1 ; NMR 1.02 ppm (3H, singlet, --CH3), 4.7-6.2 (3H, multiplet, vinyl)].

後処理

  1. customThe triethylamine and ethyl acetate are evaporated off
  2. customthe residue is purified by silica gel column chromatography (methylene chloride)
  3. customto recover 2.744 g of the above-indicated compound

出典と根拠

ORDレコード
ord-9732ec6c90284b4aa6b2e5ed0ac60a8d
出典データセット
uspto-grants-1981_05
特許番号
US04267377

反応ノート

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