Dibutylamine → 2-Amino-5-dibutylamino-1,3,4-thiadiazole
反応式
[CH2:1]([NH:5][CH2:6][CH2:7][CH2:8][CH3:9])[CH2:2][CH2:3][CH3:4].C(N(CC)CC)C.[NH2:17][C:18]1[S:19][C:20](Cl)=[N:21][N:22]=1>C(O)C>[NH2:17][C:18]1[S:19][C:20]([N:5]([CH2:6][CH2:7][CH2:8][CH3:9])[CH2:1][CH2:2][CH2:3][CH3:4])=[N:21][N:22]=1参加物
5
実験手順
28 parts of dibutylamine and 25 parts of triethylamine are added to 27 parts of 2-amino-5-chloro-1,3,4-thiadiazole in 200 parts of ethanol. The reaction mixture is heated under reflux for 2 hours and then concentrated to dryness. The residue is suspended in 250 ml of water and filtered. The 2-amino-5-dibutylamino-1,3,4-thiadiazole obtained in this manner can be recrystallised from ethanol/water. Melting point: 116°-117°
後処理
- temperatureThe reaction mixture is heated
- temperatureunder reflux for 2 hours
- concentrationconcentrated to dryness
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-eaef3371ec2a4ea4a9dec2ce4d55610d
- 出典データセット
- uspto-grants-1981_05
- 特許番号
- US04268438
反応ノート
読み込み中…