1,4-Bis(bromomethyl)benzene → 2-(bromomethyl)-2-ethylpropane-1,3-diol

温度

100 °C

2-Ethyl-2-bromomethyltrimethylene ethyl phosphite (IV), 97 grams, 0.372 mole and α,α'-dibromo-p-xylene, 48.9 grams, 0.186 mole, were mixed in a 500 ml. flask equipped with an air condenser and a nitrogen inlet tube. The mixture was slowly heated to 100° C., at which time the reaction was completed, leaving a white solid. The solid was washed with two 100 ml. portions of benzene-acetone (50/50) and then ground in a morter to a fine powder. The powder was boiled in benzene-acetone (50/50) for several minutes, cooled to 10° C., filtered and dried in a vacuum oven at 50° C. for 12 hours. There was obtained 109 grams of product, m.p. 242° C.

1. customflask equipped with an air condenser and a nitrogen inlet tube
2. customleaving a white solid
3. washThe solid was washed with two 100 ml
4. waitThe powder was boiled in benzene-acetone (50/50) for several minutes
5. temperaturecooled to 10° C.
6. filtrationfiltered
7. customdried in a vacuum oven at 50° C. for 12 hours

ORDレコード

ord-e3e46900c34a41ba8b014e714f83178d

出典データセット

uspto-grants-1981_05

DOI

10.6084/m9.figshare.5104873.v1

特許番号

US04268459