Water → 3-Acetyl-5-(1,3-benzoxazol-2-yl)-1,3,4-oxadiazol-2(3H)-one
反応式
[O:1]=[C:2]1[NH:6][N:5]=[C:4]([C:7]2[O:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[N:11]=2)[O:3]1.[C:16](OC(=O)C)(=[O:18])[CH3:17].O>C(O)(=O)C>[O:1]=[C:2]1[N:6]([C:16](=[O:18])[CH3:17])[N:5]=[C:4]([C:7]2[O:8][C:9]3[CH:15]=[CH:14][CH:13]=[CH:12][C:10]=3[N:11]=2)[O:3]1参加物
5
実験手順
5.0 g of 2-(2-oxo-3H-1,3,4-oxadiazole-5-yl)benzoxazole in 50 ml of acetic acid containing 5 ml of acetic anhydride was heated for 1 hour at 100°. The mixture was poured into water and the crystalline product filtered. Recrystallization from acetonitrile gave mp. of 231°-232°.
後処理
- filtrationthe crystalline product filtered
- customRecrystallization from acetonitrile
- customgave mp. of 231°-232°
出典と根拠
- ORDレコード
- ord-9e930962992a4f61b6499fb8d0ee0fd9
- 出典データセット
- uspto-grants-1981_05
- 特許番号
- US04269846
反応ノート
読み込み中…