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HRID 228796作成日:2026年10月26日

(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol → (4,5-Dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone

https://huagongshe.com/reaction/228796

反応式

関与物質

役割名称HCID仕込み量
反応物(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanolHCID 23078354—
触媒HCID 178418406HCID 178418406—
溶媒ChloroformHCID 6212—
生成物(4,5-Dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanoneHCID 2307824797.1%

反応手順

(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol (945 mg) was dissolved in chloroform (20 ml) to prepare a solution. Manganese dioxide (3.5 g) was added to the solution, and the mixture was stirred at room temperature overnight. The reaction solution was filtered through Celite, and the solvent was removed from the filtrate by distillation under the reduced pressure to give (4,5-dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone (910 mg, yield 97%).

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US07560558B2
出典データセットuspto-grants-2009_07
ORD IDord-ff9c0126c13c495080a3055c9946dee9
出典メモuspto-grants-2009_07