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(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol → (4,5-Dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol | HCID 23078354 | — |
| 触媒 | HCID 178418406 | HCID 178418406 | — |
| 溶媒 | Chloroform | HCID 6212 | — |
| 生成物 | (4,5-Dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone | HCID 23078247 | 97.1% |
反応手順
(4,5-Dimethylfuran-2-yl)-(4,5-dimethylthiazol-2-yl)methanol (945 mg) was dissolved in chloroform (20 ml) to prepare a solution. Manganese dioxide (3.5 g) was added to the solution, and the mixture was stirred at room temperature overnight. The reaction solution was filtered through Celite, and the solvent was removed from the filtrate by distillation under the reduced pressure to give (4,5-dimethylfuran-2-yl)(4,5-dimethylthiazol-2-yl)-methanone (910 mg, yield 97%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07560558B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-ff9c0126c13c495080a3055c9946dee9 |
| 出典メモ | uspto-grants-2009_07 |