Ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate → 4-(2,2-Dimethyl-4-p-tolyl-2H-benzo[g]chromen-7-yl)-benzoic acid
反応式
CC1SC(C2C3C(=CC4C(C=3)=C(C3C=CC(C(O)=O)=CC=3)C=CC=4)C(C)(C)CC=2)=CC=1.[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:48]=[CH:47][C:46]([CH3:49])=[CH:45][CH:44]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([O:60]CC)=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1>>[CH3:32][C:33]1([CH3:65])[CH:42]=[C:41]([C:43]2[CH:44]=[CH:45][C:46]([CH3:49])=[CH:47][CH:48]=2)[C:40]2[C:35](=[CH:36][C:37]3[CH:53]=[CH:52][C:51]([C:54]4[CH:64]=[CH:63][C:57]([C:58]([OH:60])=[O:59])=[CH:56][CH:55]=4)=[CH:50][C:38]=3[CH:39]=2)[O:34]1参加物
3
実験手順
By following the procedure employed for the preparation of 4-[1(5-methyl-thien-2-yl)3,4-dihydro-4,4-dimethyl-anthracen-8-yl]-benzoic acid (Compound 4), ethyl 4-[2,2-dimethyl-4-(tol-4-yl)-benzo(1,2-g)-chrom-3-en-7-yl]benzoate (Compound 9, 10 mg, 0.02 mmol), was converted into the title compound using LiOH in water (0.2 mL, 0.2 mmol). The title compound was obtained as an off white solid.