2-Nitrobenzoyl chloride → 2,4-Pentanedione, 3-(2-nitrobenzoyl)-
反応式
[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6](Cl)=[O:7])([O-:3])=[O:2].C[Si](C)(C)[O:15][C:16]([CH3:21])=[CH:17][C:18](=[O:20])[CH3:19]>>[N+:1]([C:4]1[CH:12]=[CH:11][CH:10]=[CH:9][C:5]=1[C:6]([CH:17]([C:18](=[O:20])[CH3:19])[C:16](=[O:15])[CH3:21])=[O:7])([O-:3])=[O:2]参加物
3
反応条件
- 温度
- 140 °C
実験手順
A mixture of 2-nitrobenzoyl chloride (500 mg) with 4-trimethylsilanyloxy-pent-3-en-2-one (540 mg) was stirred at 140° C. for 5 min. The reaction solution was cooled to room temperature and was then purified by column chromatography using acetone-hexane to give 3-(2-nitro-benzoyl)-pentane-2,4-dione (143 mg, yield 20%).
後処理
- temperatureThe reaction solution was cooled to room temperature
- customwas then purified by column chromatography
出典と根拠
- ORDレコード
- ord-141acb8f0a9d4265ae32e57ce7935bac
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07560558B2
反応ノート
読み込み中…