1H-Pyrazol-3-amine, 5-methyl- → HCID 178442661、化合物
反応式
[CH2:1]([CH:9]([C:14]([CH3:16])=O)[C:10]([O:12]C)=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[CH3:17][C:18]1[NH:22][N:21]=[C:20]([NH2:23])[CH:19]=1>C(O)CCC>[OH:12][C:10]1[N:21]2[N:22]=[C:18]([CH3:17])[CH:19]=[C:20]2[N:23]=[C:14]([CH3:16])[C:9]=1[CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]参加物
4
実験手順
200 g of methyl 2-n-octylacetoacetate and 94 g of 3(5)-amino-5(3)-methylpyrazole in 400 ml of n-butanol are refluxed for 5 hours. The mixture is cooled, and the product is filtered off under suction, washed with cold methanol and dried under reduced pressure at 60° C. to give 191 g of 7-hydroxy-2,5-dimethyl-6-n-octylpyrazolo[1,5-a]pyrimidine of melting point 199° C.
後処理
- temperatureThe mixture is cooled
- filtrationthe product is filtered off under suction
- washwashed with cold methanol
- customdried under reduced pressure at 60° C.
出典と根拠
- ORDレコード
- ord-e086054ad03f46feac43026e5f4d25a0
- 出典データセット
- uspto-grants-1986_10
- 特許番号
- US04617303
反応ノート
読み込み中…