Bromotrimethylsilane → HCID 20229905、化合物
反応式
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:19])[F:18])=[CH:13][N:12]=2)=[CH:6][C:5]=1[NH:21][CH2:22][P:23](=[O:30])([O:27]CC)[O:24]CC)([O-:3])=[O:2].C[Si](C)(C)Br>>[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]([F:20])([F:18])[F:19])=[CH:13][N:12]=2)=[CH:6][C:5]=1[NH:21][CH2:22][P:23](=[O:24])([OH:27])[OH:30])([O-:3])=[O:2]参加物
3
反応条件
- 温度
- 20 °C
実験手順
A mixture of 3 g of diethyl N-[2-nitro-5-(5-trifluoromethyl-2-pyridyloxy)phenyl]-aminomethylphosphonate and 5 g of trimethylbromosilane is stirred for 18 hours at 20° C. Excess trimethylbromosilane is removed by evaporation and the residue is then taken up in ethanol and the solution is concentrated, affording 2.51 g (96.9% of theory) of the title compound with a melting point of 94° C. (decompos.).
後処理
- customExcess trimethylbromosilane is removed by evaporation
- concentrationthe solution is concentrated