Pyridinium chloride → 3-(4-Phenyl-1,2,3,6-tetrahydro-1-pyridylmethyl)-6-hydroxy-1,2,3,4-tetrahydrocarbazole
反応式
Cl.[C:2]1([C:8]2[CH2:9][CH2:10][N:11]([CH2:14][CH:15]3[CH2:27][C:26]4[C:25]5[C:20](=[CH:21][CH:22]=[C:23]([O:28]C)[CH:24]=5)[NH:19][C:18]=4[CH2:17][CH2:16]3)[CH2:12][CH:13]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.N1C=CC=CC=1>C1(C)C=CC=CC=1.C(N(CC)CC)C>[C:2]1([C:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH:15]3[CH2:27][C:26]4[C:25]5[C:20](=[CH:21][CH:22]=[C:23]([OH:28])[CH:24]=5)[NH:19][C:18]=4[CH2:17][CH2:16]3)[CH2:10][CH:9]=2)[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1参加物
4
実験手順
A mixture of 4.19 g of 3-(4-phenyl-1,2,3,6-tetrahydro-1-pyridylmethyl)-6-methoxy-1,2,3,4-tetrahydrocarbazole hydrochloride and 3.5 g of pyridine hydrochloride is stirred at 160° for 3 hours. After the usual work-up, 3-(4-phenyl-1,2,3,6-tetrahydro-1-pyridylmethyl)-6-hydroxy-1,2,3,4-tetrahydrocarbazole, Rf 0.2 (toluene/triethylamine 9:1), is obtained.