Benzyl Chloride → HCID 178527897、化合物
反応式
C[O-].[Na+].[SH:4][C:5]1[N:9]=[C:8]([SH:10])[NH:7][N:6]=1.[CH2:11](Cl)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>CO>[CH2:11]([S:4][C:5]1[N:9]=[C:8]([SH:10])[NH:7][N:6]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1参加物
5
実験手順
Sodium methoxide (35.1 g) was added portionwise to 3,5-dimercapto-1,2,4-triazole (86.4 g) in methanol (400 ml) with stirring and cooling to 5° to 15° C. under nitrogen. After stirring for 5 minutes, the formed derivative was treated dropwise with benzyl chloride (79.7 g) at 5° to 10° C. over a period of 1 hour. The mixture was then stirred for about 20 hours at ambient temperature, then filtered. The precipitate was washed with a little ice-cold methanol, and then with water, to give 83.2 g of desired product, mp 199°-201° C.
後処理
- temperaturecooling to 5° to 15° C. under nitrogen
- stirringAfter stirring for 5 minutes
- stirringThe mixture was then stirred for about 20 hours at ambient temperature
- filtrationfiltered
- washThe precipitate was washed with a little ice-cold methanol
出典と根拠
- ORDレコード
- ord-ce1926502c4f46d896122f3d13167eba
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04795483
反応ノート
読み込み中…