Diethyl Ether → HCID 21279517、化合物
反応式
[CH2:1]([S:8][C:9]1[N:13]=[C:12]([SH:14])[NH:11][N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl[CH2:16][C:17](=O)[CH3:18].CCOCC.C(=O)(O)[O-].[Na+]>C(O)C>[CH2:1]([S:8][C:9]1[N:13]=[C:12]2[S:14][CH:16]=[C:17]([CH3:18])[N:11]2[N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
6
実験手順
The product of stage (a) (22.3 g) and chloroacetone (9.6 g) were heated in ethanol (120 ml) under reflux for 22 hours. The solution was then reduced under vacuum, and the residue was stirred with a mixture of ether and aqueous sodium bicarbonate. The ether solution was separated, washed with water, dried over magnesium sulphate, and reduced under vacuum to give 24.1 g of the desired product as an orange oil.
後処理
- temperatureunder reflux for 22 hours
- customThe ether solution was separated
- washwashed with water
- dry with materialdried over magnesium sulphate
出典と根拠
- ORDレコード
- ord-69c3e20a77984705bb93987ed50712d5
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04795483
反応ノート
読み込み中…