Dimethyl Sulfate → HCID 21279520、化合物
反応式
[CH3:1]C(C)([O-])C.[K+].[CH2:7]([S:14][C:15]1[N:16]=[C:17]2[S:22][CH:21]([CH3:23])[C:20](=[O:24])[N:18]2[N:19]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.S(OC)(OC)(=O)=O>CN(C)C=O>[CH2:7]([S:14][C:15]1[N:16]=[C:17]2[S:22][C:21]([CH3:23])=[C:20]([O:24][CH3:1])[N:18]2[N:19]=1)[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1参加物
5
実験手順
Potassium t-butoxide (2.6 g) was added to a solution of the product of stage (b) in dimethylformamide (30 ml) with stirring and cooling. After 10 minutes, this solution was treated with dimethyl sulphate (2.8 g) and stirring was continued for 4 hours. Addition to ice/water/ether and filtration gave 2.3 g of desired product, mp 101°-103° C.
後処理
- temperaturecooling
- stirringstirring
- waitwas continued for 4 hours
- additionAddition
- filtrationto ice/water/ether and filtration
出典と根拠
- ORDレコード
- ord-533e2f2f3db145cb8810a17105a99f3a
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04795483
反応ノート
読み込み中…