Hydrochloric Acid → 5-(Trifluoromethyl)isoxazol-3-ylamine
反応式
[F:1][C:2]([F:15])([F:14])[C:3]1[O:7][N:6]=[C:5]([NH:8]C(=O)N(C)C)[CH:4]=1.Cl>>[F:1][C:2]([F:15])([F:14])[C:3]1[O:7][N:6]=[C:5]([NH2:8])[CH:4]=1参加物
3
実験手順
A mixture of 5-trifluormethyl-3-dimethylcarbamoylaminoisoxazole (1.15 g, 0.005 mole) and 36% hydrochloric acid (10 eq.) were reacted at 100° C. for 10 hours. The reaction mixture was worked up in the usual way to give the crude title compound. Crude yield: 0.20 g (26%).
後処理
- customwere reacted at 100° C. for 10 hours
出典と根拠
- ORDレコード
- ord-53447d87f32b4ca29ed4f5a1e8e043b8
- 出典データセット
- uspto-grants-1989_01
- 特許番号
- US04797492
反応ノート
読み込み中…