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5-Methoxyfuran-2(5H)-one → 6,6-dimethyl-4(RS)-methoxy-3-oxabicyclo (3,1,0) hexan-2-one
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 5-Methoxyfuran-2(5H)-one | HCID 112042 | — |
| 反応物 | Diphenyl isopropylidene sulfurane | HCID 11138905 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 6,6-dimethyl-4(RS)-methoxy-3-oxabicyclo (3,1,0) hexan-2-one | HCID 12922717 | — |
反応手順
In a preferred embodiment of the invention, the alcohol ZOH is methanol and the 5(RS)-methoxy-2,5-dihydrofuran-2-one is reacted with diphenyl isopropylidene sulfurane to obtain (1RS, 5SR) 6,6-dimethyl-4(RS)-methoxy-3-oxabicyclo (3,1,0) hexan-2-one which is then subjected to acid hydrolysis to obtain (1RS, 5SR) 6,6-dimethyl-4(RS)-hydroxy-3-oxabicyclo (3,1,0) hexan-2-one.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04801723 |
| 出典データセット | uspto-grants-1989_01 |
| ORD ID | ord-d5853e3dd0a44beabb6bdd6ee24c84a4 |
| 出典メモ | uspto-grants-1989_01 |