Hydrochloric Acid → 3-Methoxy-4-phenylaminopyrrolidine hydrochloride

HRID 2293994

反応式

HRID 2293994 の反応式
C(OC([N:8]1[CH2:12][CH:11]([NH:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:10]([O:20][CH3:21])[CH2:9]1)=O)(C)(C)C.[ClH:22]>CO>[ClH:22].[CH3:21][O:20][CH:10]1[CH:11]([NH:13][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:12][NH:8][CH2:9]1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 214733421-t-Butoxycarbonyl-3-methoxy-4-phenylaminopyrrolidine

生成物 1

HCID 214733543-Methoxy-4-phenylaminopyrrolidine hydrochloride

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

In 100 ml of methanol was dissolved 1.98 g (0.0068 mole) of 1-t-butoxycarbonyl-3-methoxy-4-phenylaminopyrrolidine obtained as described above, and 23.5 ml of 6N hydrochloric acid was added thereto. The mixture was left to stand at room temperature overnight. The solvent was removed under reduced pressure, and the residue was washed with ethanol to obtain 1.71 g of 3-methoxy-4-phenylaminopyrrolidine hydrochloride as white powder.

後処理

  1. customobtained
  2. additionwas added
  3. waitThe mixture was left
  4. customThe solvent was removed under reduced pressure
  5. washthe residue was washed with ethanol

出典と根拠

ORDレコード
ord-0cc71dc497264b3cb7f2d3b3eb386623
出典データセット
uspto-grants-1997_11
特許番号
US05688791

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