Hydrochloric Acid → HCID 21473697、化合物
反応式
[CH3:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([CH2:9][N:10]2[CH2:15][CH:14]=[C:13](/[CH:16]=[CH:17]/[C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[CH2:12][CH2:11]2)=[CH:4][N:3]=1.[ClH:24]>CO.ClCCl>[ClH:24].[CH3:1][C:2]1[N:7]=[C:6]([NH2:8])[C:5]([CH2:9][N:10]2[CH2:11][CH:12]=[C:13](/[CH:16]=[CH:17]/[C:18]3[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=3)[CH2:14][CH2:15]2)=[CH:4][N:3]=1参加物
4
実験手順
A solution of 0.077 g (0.00025 mol) of (E)-2-methyl-5-(4-styryl-3,6-dihydro-2H-pyridin-1-ylmethyl)-pyrimidin-4-ylamine in 30 ml of methanol/dichloromethane 1:1 was treated with 0.07 ml (0.00026 mol) of 3.5N ethanolic hydrochloric acid. The solution was completely freed from the solvents and recrystallized from ethanol/diethyl ether. 0.046 g (54%) of (E)-2-methyl-5-(4-styryl-3,6-dihydro-2H-pyridin-1-ylmethyl)-pyrimidin-4-ylamine hydrochloride (1:1.2) was obtained as yellowish crystals; m.p. 185°-192°.