関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Tributyltin Chloride | HCID 15096 | — |
| 反応物 | Lithium diisopropylamide | HCID 2724682 | — |
| 反応物 | Phosphonic acid, 2-furanyl-, diethyl ester | HCID 12485182 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | Diethyl 5-tributylstannyl-2-furanphosphonate | HCID 22280515 | — |
反応手順
A solution of diethyl 2-furanphosphonate (1 mmol) in 2 mL THF was cooled to −78° C. and added to a solution of lithium diisopropylamide (LDA) (1 mmol) in 5 mL THF at −78° C. over 20 min. The resulting mixture was stirred −78° C. for 20 min and added into a solution of tributyltin chloride (1 mmole) in 1 mL THF at −78° C. over 20 min. The mixture was then stirred at −78° C. for 15 min, and at 25° C. for 1 h. Extraction and chromatography gave diethyl 5-tributylstannyl-2-furanphosphonate as a colorless oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 特許番号 | US07563774B2 |
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| 出典データセット | uspto-grants-2009_07 |
|---|
| ORD ID | ord-eb7d7b8bed474b9ea5a795e9cee3b814 |
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| 出典メモ | uspto-grants-2009_07 |
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