Isopropyl iodide → HCID 21474510、化合物

HRID 2294586ノート

反応式

HRID 2294586 の反応式
[C:1]([C:5]1[CH:6]=[C:7]([CH:18]=[CH:19][C:20]=1[OH:21])[C:8]([O:10][CH2:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:9])([CH3:4])([CH3:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+].I[CH:29]([CH3:31])[CH3:30]>C(C(C)=O)C>[C:1]([C:5]1[CH:6]=[C:7]([CH:18]=[CH:19][C:20]=1[O:21][CH:29]([CH3:31])[CH3:30])[C:8]([O:10][CH2:11][C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)=[O:9])([CH3:4])([CH3:2])[CH3:3]

参加物

5

反応物 3

HCID 6362Isopropyl iodideHCID 11430Potassium CarbonateHCID 21474535HCID 21474535、化合物

生成物 1

HCID 21474510HCID 21474510、化合物

試薬・触媒・溶媒 1

HCID 6569Methyl Ethyl Ketone溶媒

実験手順

5.7 g (0.02 mol) of benzyl 3-tert-butyl-4-hydroxybenzoate, 7 g (0.05 mol) of finely ground potassium carbonate, 4 ml (0.04 mol) of 2-iodopropane and 100 ml of methyl ethyl ketone are introduced under nitrogen into a three-necked flask. The mixture is heated to reflux for 24 h, the inorganic matter is filtered off and the filtrate is evaporated. The residue is taken up with ethyl ether and water and the organic phase is separated after settling has taken place, dried over magnesium sulphate and evaporated.

後処理

  1. temperatureThe mixture is heated
  2. temperatureto reflux for 24 h
  3. filtrationthe inorganic matter is filtered off
  4. customthe filtrate is evaporated
  5. customthe organic phase is separated after settling
  6. dry with materialdried over magnesium sulphate
  7. customevaporated

出典と根拠

ORDレコード
ord-fbfe486d07a84a838ab5c938d20c2295
出典データセット
uspto-grants-1997_11
特許番号
US05688817

反応ノート

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