Ethyl isocyanate → (E,E)-4-ethyl-2,4-hexadien-1-yl ethylcarbamate
反応式
[CH2:1](/[C:3](=[CH:8]\[CH3:9])/[CH:4]=[CH:5]/[CH2:6][OH:7])[CH3:2].[CH2:10]([N:12]=[C:13]=[O:14])[CH3:11]>ClCCCl>[CH2:10]([NH:12][C:13](=[O:14])[O:7][CH2:6]/[CH:5]=[CH:4]/[C:3](/[CH2:1][CH3:2])=[CH:8]/[CH3:9])[CH3:11]参加物
4
実験手順
A solution of (E,E)-4-ethyl-2,4-hexadien-1-ol (2.0 g) and ethyl isocyanate (1.13 g) in 1,2-dichloroethane (12 ml) was stirred at 0° C. for 3 hours and at room temperature for 12 hours. The reaction mixture was washed with water and brine, dried over anhydrous magnesium sulfate, and evaporated in vacuo. The residue was chromatographed on silica gel (chloroform) to give (E,E)-4-ethyl-2,4-hexadien-1-yl ethylcarbamate (2.5 g) as an oil.
後処理
- washThe reaction mixture was washed with water and brine
- dry with materialdried over anhydrous magnesium sulfate
- customevaporated in vacuo
- customThe residue was chromatographed on silica gel (chloroform)
出典と根拠
- ORDレコード
- ord-93dddf0de3ea4d44842bbb8a78b3c7a2
- 出典データセット
- uspto-grants-1997_11
- 特許番号
- US05691366
反応ノート
読み込み中…