Phosgene → 2-Chloro-3-pyridinesulfonylisocyanate

HRID 2295249ノート

反応式

HRID 2295249 の反応式
[Cl:1][C:2]1[C:7]([S:8]([NH:11][C:12](=[O:18])NCCCC)(=[O:10])=[O:9])=[CH:6][CH:5]=[CH:4][N:3]=1.C(Cl)(Cl)=O>C1(C)C(C)=CC=CC=1>[Cl:1][C:2]1[C:7]([S:8]([N:11]=[C:12]=[O:18])(=[O:9])=[O:10])=[CH:6][CH:5]=[CH:4][N:3]=1

参加物

4

反応物 2

HCID 6371PhosgeneHCID 12383441HCID 12383441、化合物

生成物 1

HCID 130384352-Chloro-3-pyridinesulfonylisocyanate

試薬・触媒・溶媒 1

HCID 7237O-Xylene溶媒

実験手順

To 125 ml of dry xylene was added with stirring 20.7 g of 2-chloro-N-(butylcarbamoyl)-3-pyridinesulfonamide. This solution was heated to reflux, and phosgene added until no further uptake of this gas was observed. It was then cooled, filtered and the solvent removed in vacuo to yield 2-chloro-3-pyridinesulfonylisocyanate as an oil Bp 108°-110° (0.7 mm Hg) and showing a sharp absorption peak in the infrared region at 2220 cm-1.

後処理

  1. temperatureThis solution was heated
  2. temperatureto reflux
  3. temperatureIt was then cooled
  4. filtrationfiltered
  5. customthe solvent removed in vacuo

出典と根拠

ORDレコード
ord-2e145d4127e149cc899d0287e6686521
出典データセット
uspto-grants-1984_01
特許番号
US04424073

反応ノート

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