Tert-Butylhydroquinone → HCID 54443355、化合物

HRID 2295331ノート

反応式

HRID 2295331 の反応式
[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH2:5].[CH:7]([C:9]1[O:10][C:11](=[O:16])[C:12]([CH3:15])([CH3:14])[N:13]=1)=[CH2:8].O1C=CNC1=O.C(C1C=C(O)C=CC=1O)(C)(C)C>C1C=CC=CC=1>[CH3:1][N:2]([CH3:6])[CH2:3][CH2:4][NH:5][C:11](=[O:16])[C:12]([CH3:15])([NH:13][C:9](=[O:10])[CH:7]=[CH2:8])[CH3:14]

参加物

6

反応物 4

HCID 16043Tert-ButylhydroquinoneHCID 66053N,N-DimethylethylenediamineHCID 1861144-Oxazolin-2-oneHCID 98127942-Ethenyl-4,4-dimethyl-1,3-oxazol-5(4H)-one

生成物 1

HCID 54443355HCID 54443355、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒2 回

実験手順

A solution of 100 g. of N,N-dimethylethylenediamine in 40 cc. of benzene was added dropwise to a stirring solution of 16.4 g. of 2-vinyl-4,4-dimethyl-5-oxazolone in 50 cc. of benzene. The oxazolone solution contained a few milligrams of t-butylhydroquinone as a polymerization inhibitor. An external water bath was used to maintain the resultant solution at about 25° C. The solution was stirred about 2 hours, filtered through Celite, and evaporated. The residue after evaporation was triturated with hexane and the mixture filtered to provide N-(N',N'-dimethyl-β-aminoethyl)-2-methyl-2-acrylamidopropanoic acid amide as a white solid.

後処理

  1. customAn external water bath was used
  2. filtrationfiltered through Celite
  3. customevaporated
  4. customThe residue after evaporation
  5. customwas triturated with hexane
  6. filtrationthe mixture filtered

出典と根拠

ORDレコード
ord-f684a47319c144afa7e7365e4b62a48c
出典データセット
uspto-grants-1984_01
特許番号
US04424272

反応ノート

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