Hydrochloric Acid → Ethyl 7-hydroxynaphthalene-2-carboxylate
反応式
[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([C:12]([OH:14])=[O:13])=[CH:9]2)=[CH:4][CH:3]=1.Cl.[CH2:16](O)[CH3:17]>>[OH:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([C:12]([O:14][CH2:16][CH3:17])=[O:13])=[CH:9]2)=[CH:4][CH:3]=1参加物
4
実験手順
A solution of 7-hydroxynaphthalene-2-carboxylic acid (56.09 g) in ethanol (200 ml) was saturated with dry hydrogen chloride and then refluxed for 30 minutes. The mixture was evaporated to about half volume, treated with water, and extracted with ethyl acetate, which was washed with water, and sodium bicarbonate solution, dried and evaporated to give a solid. Crystallisation from ethyl acetate afforded ethyl 7-hydroxynaphthalene-2-carboxylate (37.5 g), m.p. 155°-156°.
後処理
- temperaturerefluxed for 30 minutes
- customThe mixture was evaporated to about half volume
- additiontreated with water
- extractionextracted with ethyl acetate, which
- washwas washed with water, and sodium bicarbonate solution
- customdried
- customevaporated
- customto give a solid
- customCrystallisation from ethyl acetate
出典と根拠
- ORDレコード
- ord-89b06af337364db2ae9652671b829b71
- 出典データセット
- uspto-grants-1984_01
- 特許番号
- US04424231
反応ノート
読み込み中…