Triethylamine → N-[2-(1,2-dichlorovinyloxy)phenylsulfonyl]-N'-methylurea

HRID 2295469ノート

反応式

HRID 2295469 の反応式
[Cl:1][C:2]([O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[S:12]([NH2:15])(=[O:14])=[O:13])=[CH:3][Cl:4].[CH3:16][N:17]=[C:18]=[O:19].C(N(CC)CC)C>C(Cl)Cl>[Cl:1][C:2]([O:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[S:12]([NH:15][C:18]([NH:17][CH3:16])=[O:19])(=[O:13])=[O:14])=[CH:3][Cl:4]

参加物

5

反応物 3

HCID 8471TriethylamineHCID 12228Methyl IsocyanateHCID 537128512-[(1,2-Dichloroethenyl)oxy]benzene-1-sulfonamide

生成物 1

HCID 54175902N-[2-(1,2-dichlorovinyloxy)phenylsulfonyl]-N'-methylurea

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A suspension of 6.7 g of 2-(1,2-dichlorovinyloxy)phenylsulfonamide in 50 ml of methylene chloride is treated with 1.9 g of methyl isocyanate. 3.3 g of triethylamine are added dropwise to this mixture at a temperature of 20°-25° C. within 10 minutes resulting in a clear solution. The solution is stirred for a further hour and evaporated to dryness. The residue is solved in 5% aqueous sodium carbonate and acidified with a 10% solution of hydrochloric acid yielding 7.8 g of N-[2-(1,2-dichlorovinyloxy)-phenylsulfonyl]-N'-methyl urea, m.p. 225°-226° C.

後処理

  1. customresulting in a clear solution
  2. customevaporated to dryness

出典と根拠

ORDレコード
ord-efaa04ec5e9445609acef31235708e6a
出典データセット
uspto-grants-1984_01
特許番号
US04425154

反応ノート

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