Methylamine → HCID 178484993、化合物
反応式
[C:1]([NH:3][C:4](=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[C:17]([O:18][CH3:19])=[CH:16][CH:15]=[CH:14][N:13]=1)SC)#[N:2].[CH3:20][NH2:21]>C(O)C>[C:1]([NH:3][C:4]([NH:21][CH3:20])=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[C:17]([O:18][CH3:19])=[CH:16][CH:15]=[CH:14][N:13]=1)#[N:2]参加物
4
実験手順
N-cyano-N'-[2-((3-methoxy-2-pyridyl)methylthio)ethyl]-S-methylisothiourea (1.9 g) in ethanol (10 ml) was treated with ethanolic methylamine (20 ml 33% solution) and the resultant clear solution was allowed to stand overnight. Excess of methylamine was removed by bubbling nitrogen through the solution and the crystalline precipitate was recrystallised from ethanol to yield the title product (1.2 g), m.p. 122°-123°.
後処理
- customExcess of methylamine was removed
- customby bubbling nitrogen through the solution
- customthe crystalline precipitate was recrystallised from ethanol
出典と根拠
- ORDレコード
- ord-b78501f23fda4d76ad7ad11cf35a7048
- 出典データセット
- uspto-grants-1984_01
- 特許番号
- US04426526
反応ノート
読み込み中…