Triphenylphosphine → (4-(Ethoxycarbonyl)benzyl)triphenylphosphonium bromide

HRID 2296044ノート

反応式

HRID 2296044 の反応式
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:20][CH2:21][C:22]1[CH:32]=[CH:31][C:25]([C:26]([O:28][CH2:29][CH3:30])=[O:27])=[CH:24][CH:23]=1>C1C=CC=CC=1>[Br-:20].[CH2:29]([O:28][C:26]([C:25]1[CH:24]=[CH:23][C:22]([CH2:21][P+:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)=[CH:32][CH:31]=1)=[O:27])[CH3:30]

参加物

4

反応物 2

HCID 11776TriphenylphosphineHCID 954261Ethyl 4-(bromomethyl)benzoate

生成物 1

HCID 16236583(4-(Ethoxycarbonyl)benzyl)triphenylphosphonium bromide収率 74.9%

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

A mixture of 16 g of triphenylphosphine, 13.35 g of ethyl 4-bromomethylbenzoate and 50 ml of benzene was stirred at room temperature for 2 days. The precipitate was filtered off, and dried in vacuo to give 20.8 g of (4-ethoxycarbonylbenzyl)triphenylphosphonium bromide.

後処理

  1. filtrationThe precipitate was filtered off
  2. customdried in vacuo

出典と根拠

ORDレコード
ord-10f1ae07c4b845d0a06a06658e9c4870
出典データセット
uspto-grants-1984_01
特許番号
US04427682

反応ノート

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