Ethanol → 5'-Amino-1'-phenyl-[2,3'-bipyridin]-6'(1'H)-one
反応式
C(O)C.[N+:4]([C:7]1[C:8](=[O:25])[N:9]([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[CH:12]=1)([O-])=O>[H][H].[C].[Pd]>[NH2:4][C:7]1[C:8](=[O:25])[N:9]([C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:10]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[CH:12]=1参加物
5
実験手順
100 mg of 10% palladium-carbon was added to 20 ml of an ethanol solution containing 546 mg of 3-nitro-1-phenyl-5-(pyridin-2-yl)-1,2-dihydropyridin-2-one, followed by stirring overnight in hydrogen atmosphere. The reaction mixture was filtered through silica gel and concentrated, to give 411 mg of the title compound.
後処理
- filtrationThe reaction mixture was filtered through silica gel
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-8097c69d60324cfea34958ef5b74cc03
- 出典データセット
- uspto-grants-2009_07
- 特許番号
- US07563811B2
反応ノート
読み込み中…