Isobutyryl chloride → 7-Bromo-1-(propan-2-yl)-3,4-dihydroisoquinoline

反応式

[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][NH2:10])=[CH:4][CH:3]=1.[CH3:11][CH:12]([CH3:16])[C:13](Cl)=O>>[Br:1][C:2]1[CH:7]=[C:6]2[C:5]([CH2:8][CH2:9][N:10]=[C:11]2[CH:12]([CH3:16])[CH3:13])=[CH:4][CH:3]=1

参加物

反応物 2

HCID 62325Isobutyryl chloride

HCID 533915p-Bromophenethylamine

生成物 1

HCID 186800687-Bromo-1-(propan-2-yl)-3,4-dihydroisoquinoline

実験手順

The desired product was prepared from 2-(4-bromophenyl)ethylamine and 2-methylpropanoyl chloride according to the procedure described in J. Org. Chem. 1991, 56, 6034.

出典と根拠

ORDレコード: ord-a530e05f30a947d084b7da9c08876ba1
出典データセット: uspto-grants-2002_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06495562B1

反応ノート

読み込み中…