化工社化工社 化学情報印刷レポート · 研究参考用
Dimethyl Pentadecanedioate → Methyl 15-Hydroxypentadecanoate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Dimethyl Pentadecanedioate | HCID 11415366 | — |
| 反応物 | HCID 178418361 | HCID 178418361 | — |
| 触媒 | Chromium, compd. with copper (1:1) | HCID 9833946 | — |
| 生成物 | Methyl 15-Hydroxypentadecanoate | HCID 3496889 | 35% |
反応手順
150 g (499 mmol) of dimethyl 1,15-pentadecandioate and 750 mg (0.5% by weight per the diester) of a commercial copper-chromium catalyst (content of copper as copper oxides: 42% by weight) were added to an autoclave and subjected to hydrogenation reaction at the hydrogen pressure of 20.0 Mpa at 280° C. After 2 hours, methyl 15-hydroxypentadecanoate was obtained in 35% yield. The degree of the conversion was 67% the selectivity was 53%, and the yield was 35%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06495706B2 |
| 出典データセット | uspto-grants-2002_12 |
| ORD ID | ord-a9ac413624b5490cabdb2384afb428f9 |
| 出典メモ | uspto-grants-2002_12 |