Ammonia → Urea, N,N'-bis(phenylmethyl)-

HRID 2300036

反応式

HRID 2300036 の反応式
[NH2:1][C:2]([NH2:4])=[O:3].[CH2:5](N)[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1.N>>[CH2:5]([NH:1][C:2]([NH:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1)=[O:3])[C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][CH:7]=1

参加物

4

反応物 3

HCID 222AmmoniaHCID 1176UreaHCID 7504Benzylamine

生成物 1

HCID 72889Urea, N,N'-bis(phenylmethyl)-収率 599.4%

実験手順

Heated was a mixture of urea 5.84 g (9.72 mmol) and benzylamine 25.0 g (23.3 mmol, 2.4 equivalents) at 150° C.-155° C. for 5 hours attaching with an air cooler. During the heating, observed was the ammonia gas evolution from colorless liquid reaction mixture. By cooling, it turned solidified at around room temperature. Purified was the reaction product by recrystallization from ethanol-benzene (1:1 mixture) to give N,N′-dibenzylurea 14.0 g as white fine needles (59.9% yield).

後処理

  1. temperatureHeated
  2. customfrom colorless liquid reaction mixture
  3. temperatureBy cooling
  4. customturned solidified at around room temperature
  5. customPurified
  6. customby recrystallization from ethanol-benzene (1:1 mixture)

出典と根拠

ORDレコード
ord-2828b789b1a44f70be3e7ce81ebdc615
出典データセット
uspto-grants-2002_12
特許番号
US06498164B1

関連ノート

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