Ethyl 2-chloroisonicotinate → Ethyl 2-(3,5-dimethoxy-4-isopropoxyphenyl)isonicotinate
反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5](B(O)O)[CH:6]=[C:7]([O:13][CH3:14])[C:8]=1[O:9][CH:10]([CH3:12])[CH3:11].Cl[C:19]1[CH:20]=[C:21]([CH:27]=[CH:28][N:29]=1)[C:22]([O:24][CH2:25][CH3:26])=[O:23]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([C:19]2[CH:20]=[C:21]([CH:27]=[CH:28][N:29]=2)[C:22]([O:24][CH2:25][CH3:26])=[O:23])[CH:6]=[C:7]([O:13][CH3:14])[C:8]=1[O:9][CH:10]([CH3:12])[CH3:11]参加物
3
実験手順
To a solution of 3,5-dimethoxy-4-isopropoxyphenylboronic acid (1.23 g) and ethyl 2-chloroisonicotinate (0.95 g) were condensed in the same manner as described in Preparation Example 1 to give the title compound.
後処理
- customcondensed in the same manner
- customas described in Preparation Example 1
出典と根拠
- ORDレコード
- ord-d7504201b3764722bf289f8fd9dc4567
- 出典データセット
- uspto-grants-2002_12
- 特許番号
- US06498169B1
反応ノート
読み込み中…