p-METHYLACETOPHENONE → 1-(4-Methylphenyl)butane-1,3-dione
反応式
[C:1]1([C:7](=[O:13])[CH2:8][C:9](=[O:12])[CH2:10]C)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:14]C1C=CC(C(=O)C)=CC=1>CCOC(C)=O>[CH3:14][C:4]1[CH:3]=[CH:2][C:1]([C:7](=[O:13])[CH2:8][C:9](=[O:12])[CH3:10])=[CH:6][CH:5]=1参加物
4
実験手順
The title compound was prepared (as described above for Intermediate 16) from 2.0 g of 4′-methylacetophenone and 2.9 mL of EtOAc to yield 1.68 grams of Intermediate 27: TLC analysis: Rf=0.61 (5/1, hexanes/EtOAc), 1H NMR (400 MHz, CDCl3, enol form) δ7.72 (d, 2H, J=8.2), 7.24 (d, 2H, J=7.4), 6.15 (s, 1H), 2.4 (s, 3H), 2.2 (s, 3H).
出典と根拠
- ORDレコード
- ord-2dd7bc46806046b89bb8cc269bb9304d
- 出典データセット
- uspto-grants-2002_12
- 特許番号
- US06498174B1
反応ノート
読み込み中…