関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Diethylamine | HCID 8021 | — |
| 反応物 | Benzoic acid, 3-(chlorosulfonyl)- | HCID 77641 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 3-(Diethylsulfamoyl)benzoic acid | HCID 794595 | — |
反応手順
To a solution of 3-(chlorosulfonyl)benzoic acid (1.02 g, 4.62 mmol) in CH2Cl2 (100 mL) at 0° C. was added diethylamine (2.4 mL, 23 mmol). The resulting mixture was stirred at 0° C. for 3 h then worked up by adding 2N aqueous HCl and extracting 3× with EtOAc. The combined organic was washed with brine then dried over MgSO4 and concentrated under reduced pressure. The residue was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06498165B1 |
|---|
| 出典データセット | uspto-grants-2002_12 |
|---|
| ORD ID | ord-90ed747076b34b5eba680df517cd9781 |
|---|
| 出典メモ | uspto-grants-2002_12 |
|---|
