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3,5-Difluorophenylacetic acid → HCID 10391797、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3,5-Difluorophenylacetic acid | HCID 145424 | — |
| 反応物 | 2-(1-Aminoethyl)-1-tert-butoxycarbonyl-4-methoxycarbonyl-4-phenylmethyl-2-imidazoline | HCID 22592461 | — |
| 生成物 | HCID 10391797 | HCID 10391797 | — |
反応手順
Following General Procedure C above and using 3,5-difluorophenylacetic acid (Aldrich) and 1-tert-butoxycarbonyl-2-(1-aminoethyl)-4-methoxycarbonyl-4-phenylmethyl-2-imidazoline (Example J), the title compound was prepared as an amorphous solid. The reaction was monitored by tlc (Rf=0.34 in 2:1 hexanes/EtOAc) and the product was purified by flash column chromatography.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06849650B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-5ab1731a61c04d56b1d251826165876c |
| 出典メモ | uspto-grants-2005_02 |