化工社化工社 化学情報印刷レポート · 研究参考用
DL-alanine → 2-Methylpropyl 2-aminopropanoate hydrochloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | DL-alanine | HCID 602 | — |
| 反応物 | Isobutanol | HCID 6560 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | 2-Methylpropyl 2-aminopropanoate hydrochloride | HCID 86200109 | — |
反応手順
A mixture of 35.64 g (0.4 mol) of D,L-alanine (Aldrich), 44 mL (0.6 mol) of thionyl chloride (Aldrich) and 200 mL of iso-butanol was refluxed for 1.5 hours. The volatiles were removed at reduced pressure at 90° C. under reduced pressure to give the title compound as an oil, which was used without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06849650B2 |
| 出典データセット | uspto-grants-2005_02 |
| ORD ID | ord-4925e8544ee04f8dbe2b5bf9ea58b95b |
| 出典メモ | uspto-grants-2005_02 |