HCID 18462590、化合物 → [1-Benzyl-7-(4-aminobutoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester

HRID 2301980ノート

反応式

HRID 2301980 の反応式
COC(=O)CC1CC2C(=CC(OCCNC(OC(C)(C)C)=O)=CC=2)NC1=O.[CH3:28][O:29][C:30](=[O:63])[CH2:31][C:32]1[C:33](=[O:62])[N:34]([CH2:55][C:56]2[CH:61]=[CH:60][CH:59]=[CH:58][CH:57]=2)[C:35]2[C:40]([CH:41]=1)=[CH:39][CH:38]=[C:37]([O:42][CH2:43][CH2:44][CH2:45][CH2:46][NH:47]C(OC(C)(C)C)=O)[CH:36]=2>>[CH3:28][O:29][C:30](=[O:63])[CH2:31][C:32]1[C:33](=[O:62])[N:34]([CH2:55][C:56]2[CH:57]=[CH:58][CH:59]=[CH:60][CH:61]=2)[C:35]2[C:40]([CH:41]=1)=[CH:39][CH:38]=[C:37]([O:42][CH2:43][CH2:44][CH2:45][CH2:46][NH2:47])[CH:36]=2

参加物

3

反応物 2

HCID 18462590HCID 18462590、化合物HCID 69979482[7-(4-tert-Butoxycarbonylaminobutoxy)-1-benzyl-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester

生成物 1

HCID 69978004[1-Benzyl-7-(4-aminobutoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester

実験手順

The title compound is prepared according to the procedure of Example 78 except that [7-(2-tert-butoxycarbonylamino-ethoxy)-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-acetic acid methyl ester is replaced with [7-(4-tert-butoxycarbonylaminobutoxy)-1-benzyl-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.

出典と根拠

ORDレコード
ord-1a0f36967a744b31a7803821fdca9193
出典データセット
uspto-grants-2002_08
特許番号
US06429214B1

反応ノート

読み込み中…