[7-(3-tert-Butoxycarbonylaminopropoxy)-1-ethyl-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester → [1-Ethyl-7-(3-aminopropoxy)-2-oxo-1,2-dihydro-quinolin-3-yl]acetic Acid Methyl Ester
反応式
COC(=O)CC1CC2C(=CC(OCC(N=C=O)OC(C)(C)C)=CC=2)NC1=O.[CH3:28][O:29][C:30](=[O:57])[CH2:31][C:32]1[C:33](=[O:56])[N:34]([CH2:54][CH3:55])[C:35]2[C:40]([CH:41]=1)=[CH:39][CH:38]=[C:37]([O:42][CH2:43][CH2:44][CH2:45][NH:46]C(OC(C)(C)C)=O)[CH:36]=2>>[CH3:28][O:29][C:30](=[O:57])[CH2:31][C:32]1[C:33](=[O:56])[N:34]([CH2:54][CH3:55])[C:35]2[C:40]([CH:41]=1)=[CH:39][CH:38]=[C:37]([O:42][CH2:43][CH2:44][CH2:45][NH2:46])[CH:36]=2参加物
3
反応物 2
生成物 1
実験手順
The title compound is prepared according to the procedure of Example 78 except that [7-(2-tert-butoxy-carbonylamino-ethoxy)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]acetic acid methyl ester is replaced with [7-(3-tert-butoxycarbonylaminopropoxy)-1-ethyl-2-oxo-1,2-dihydro-quinolin-3-yl]acetic acid methyl ester.