関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Acetic Acid | HCID 176 | — |
| 反応物 | Butanedione | HCID 650 | — |
| 反応物 | 1,3-Dimethyladamantane | HCID 12800 | — |
| 触媒 | Cobalt diacetate | HCID 6277 | — |
| 生成物 | 3,5-Dimethyl-1-adamantanol | HCID 265793 | 6% |
| 生成物 | 1-Acetyl-3,5-dimethyl Adamantane | HCID 12113124 | 40% |
| 生成物 | 1,3-Diacetyl-5,7-dimethyladamantane | HCID 12113141 | 15% |
| 生成物 | 1,3-Dimethyl-4-adamantanone | HCID 12644332 | 4% |
反応手順
A mixture of 3 mmol of 1,3-dimethyladamantane, 18 mmol of biacetyl, 0.015 mmol of cobalt (II) acetate, and 3 ml of acetic acid was stirred at 60° C. under an oxygen atmosphere (1 atm) for 4 hours. Gas chromatographic analysis of products in the reaction mixture revealed that 1,3-dimethyladamantane was converted, at a rate of 93%, to 1-acetyl-3,5-dimethyladamantane (yield 40%), 1,3-diacetyl-5,7-dimethyladamantane (yield 15%), 1-acetyl-3,5-d-methyl-7-adamantanol (yield 5%), 1,3-dimethyl-5-adamantanol (yield 6%), and 1,3-dimethyl-4-adamantanone (yield 4%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06429314B1 |
|---|
| 出典データセット | uspto-grants-2002_08 |
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| ORD ID | ord-bd1167e0930d4c7e884b10f8d5118839 |
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| 出典メモ | uspto-grants-2002_08 |
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