関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Butanedione | HCID 650 | — |
| 反応物 | N-Hydroxyphthalimide | HCID 10665 | — |
| 反応物 | 1,3-Dimethyladamantane | HCID 12800 | — |
| 触媒 | Cobalt diacetate | HCID 6277 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 1-Acetyl-3,5-dimethyl Adamantane | HCID 12113124 | 58% |
| 生成物 | 1-Acetyl-3,5-dimethyl-7-adamantanol | HCID 13464074 | 22% |
反応手順
A mixture of 3 mmol of 1,3-dimethyladamantane, 18 mmol of biacetyl, 0.3 mmol of N-hydroxyphthalimide, 0.015 mmol of cobalt (II) acetate, and 3 ml of acetic acid was stirred at 75° C. under an oxygen atmosphere (1 atm) for 8 hours. Products in the reaction mixture were found, by gas chromatographic analysis, to be 1-acetyl-3,5-dimethyladamantane (yield 58%), and 1-acetyl-3,5-dimethyl-7-adamantanol (yield 22%) at a conversion rate of 1,3-dimethyladamantane of 94%.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US06429314B1 |
|---|
| 出典データセット | uspto-grants-2002_08 |
|---|
| ORD ID | ord-a56293a0b6aa4cf699400b44623797c9 |
|---|
| 出典メモ | uspto-grants-2002_08 |
|---|
