5-Bromoindole → 5-Bromo-1-methyl-1H-indole

反応式

[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.Br[C:12]1C=CC=C2C=1N(C)C=C2.BrC1C=CC=C2C=1NC=C2>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([CH3:12])[CH:6]=[CH:5]2

参加物

反応物 3

HCID 249055-Bromoindole

HCID 27570207-Bromoindole

HCID 219500697-Bromo-1-methyl-1H-indole

生成物 1

HCID 2857575-Bromo-1-methyl-1H-indole

実験手順

5-Bromo-1-methylindole was prepared from 5-bromoindole as described for the preparation of 7-bromo-1-methylindole from 7-bromoindole. Purification by chromatography using EtOAc:petroleum ether 1:10

後処理

customPurification by chromatography

出典と根拠

ORDレコード: ord-11e7f7713be74a2c9c1624301c833944
出典データセット: uspto-grants-2002_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06432962B1

反応ノート

読み込み中…