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2-(4-Iodophenoxy)pyrimidine → HCID 57762617、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-(4-Iodophenoxy)pyrimidine | HCID 1484617 | — |
| 反応物 | 2-(2,6-Dichlorobenzamido)pent-4-enoic acid methyl ester | HCID 57762518 | — |
| 生成物 | HCID 57762617 | HCID 57762617 | 62.3% |
反応手順
In the same manner as in Example 1, 2-(2,6-dichlorobenzamido)pent-4-enoic acid methyl ester (54.4 mg) was reacted with 2-(4-iodophenoxy)pyrimidine (59.2 mg) to obtain (E)-2-(2,6-dichlorobenzamido)-5-[4-(pyrimidin-2-yloxy)phenyl]pent-4-enoic acid methyl ester (53.0 mg). Thin layer chromatography (silica gel, mobile phase: cyclohexane/ethyl acetate=10/1) was used for purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07566724B2 |
| 出典データセット | uspto-grants-2009_07 |
| ORD ID | ord-febf8f04efc44469adbcdb550a454e05 |
| 出典メモ | uspto-grants-2009_07 |