Hydrochloric Acid → [4-(4-Methoxyphenyl)-5-(3-pyridyl)-1,3-thiazol-2-yl]amine hydrochloride

HRID 2304601

反応式

HRID 2304601 の反応式
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]=[C:11]([NH2:20])[S:12][C:13]=2[C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[CH:5][CH:4]=1.[ClH:21]>CO>[ClH:21].[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:9]2[N:10]=[C:11]([NH2:20])[S:12][C:13]=2[C:14]2[CH:15]=[N:16][CH:17]=[CH:18][CH:19]=2)=[CH:7][CH:8]=1

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 30248942-Thiazolamine, 4-(4-methoxyphenyl)-5-(3-pyridinyl)-

生成物 1

HCID 13518884[4-(4-Methoxyphenyl)-5-(3-pyridyl)-1,3-thiazol-2-yl]amine hydrochloride収率 80%

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

[4-(4-Methoxyphenyl)-5-(3-pyridyl)-I,3-thiazol-2-yl]amine (200 mg) was dissolved in 1% methanol solution of hydrogen chloride (3.2 mL), and the solvent was evaporated. The crude crystalline was recrystallized from methanol-ethyl acetate to give the title compound (180 mg, yield 80%).

後処理

  1. customthe solvent was evaporated
  2. customThe crude crystalline was recrystallized from methanol-ethyl acetate

出典と根拠

ORDレコード
ord-13c24b961baf4383b40f79de26b556b2
出典データセット
uspto-grants-2002_08
特許番号
US06436966B1

関連ノート

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