Isobutyric Acid → Tetramethylammonium Isobutyrate

反応式

[C:1]([OH:6])(=[O:5])[CH:2]([CH3:4])[CH3:3].[OH-].[CH3:8][N+:9]([CH3:12])([CH3:11])[CH3:10]>>[C:1]([O-:6])(=[O:5])[CH:2]([CH3:4])[CH3:3].[CH3:8][N+:9]([CH3:12])([CH3:11])[CH3:10]

参加物

反応物 2

HCID 6590Isobutyric Acid

HCID 60966Tetramethylammonium hydroxide

生成物 1

HCID 21900158Tetramethylammonium Isobutyrate

実験手順

To a 20 L round bottom flask was added isobutyric acid (1300 mL, 14 mol), and an aqueous solution of 25% tetramethylammonium hydroxide (5 L, 14 mol). The water was removed under reduced pressure and azeotroped with toluene (2×2 L) to leave the product (13) as an amber liquid, which was used without further purification.

後処理

customThe water was removed under reduced pressure
customazeotroped with toluene (2×2 L)

出典と根拠

ORDレコード: ord-d9bf35d5d3d148af934671ce2361fb16
出典データセット: uspto-grants-2009_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07566738B2

反応ノート

読み込み中…

参加物