1-(3,5-difluoro-benzyl)-1H-indazol-5-ylamine → (1-(3,5-Difluoro-benzyl)-1H-indazol-5-yl)-(6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazolin-4-yl)amine hydrochloride
反応式
[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[C:17]([F:19])[CH:18]=1)[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([NH2:15])=[CH:12][CH:13]=2)[CH:8]=[N:7]1.[Cl:20][C:21]1[C:30]2[C:25](=[CH:26][CH:27]=[C:28]([C:31]3[O:32][C:33]([CH3:36])=[N:34][N:35]=3)[CH:29]=2)[N:24]=[CH:23][N:22]=1>>[ClH:20].[F:1][C:2]1[CH:3]=[C:4]([CH:16]=[C:17]([F:19])[CH:18]=1)[CH2:5][N:6]1[C:14]2[C:9](=[CH:10][C:11]([NH:15][C:21]3[C:30]4[C:25](=[CH:26][CH:27]=[C:28]([C:31]5[O:32][C:33]([CH3:36])=[N:34][N:35]=5)[CH:29]=4)[N:24]=[CH:23][N:22]=3)=[CH:12][CH:13]=2)[CH:8]=[N:7]1参加物
3
実験手順
The title compound was prepared according to Procedure A from 1-(3,5-difluoro-benzyl)-1H-indazol-5-ylamine and 4-chloro-6-(5-methyl-1,3,4-oxadiazol-2-yl)-quinazoline; δH [2H6]DMSO 12.50(1H, bs), 10.35(1H, s), 9.25(1H, s), 8.61(1H, s), 8.35(1H, m), 8.22(2H, m), 7.88(1H, dd), 7.75(2H, m), 7.16(1H, m), 6.93(1H, m), 5.73(2H, s), 2.67(3H, s); m/z (M+1+) 470.
出典と根拠
- ORDレコード
- ord-f83eabe8d037415c82905fd01602618e