Propargylamine → 3-(3-(Trifluoromethyl)phenyl)-N-(2-propynyl)azetidine-1-carboxamide
反応式
[F:1][C:2]([F:27])([F:26])C1C=C(C2CN(C(C3C=CC=CC=3)C3C=CC=CC=3)C2)C=CC=1.C(N)C#C.C([C:36]1[CH:41]=[CH:40][C:39]([CH:42]2[CH2:45][N:44]([C:46]([NH:48][CH2:49][CH:50]=[CH2:51])=[O:47])[CH2:43]2)=[CH:38][CH:37]=1)(C)(C)C>>[F:1][C:2]([F:27])([F:26])[C:41]1[CH:40]=[C:39]([CH:42]2[CH2:43][N:44]([C:46]([NH:48][CH2:49][C:50]#[CH:51])=[O:47])[CH2:45]2)[CH:38]=[CH:37][CH:36]=1参加物
4
実験手順
This product was prepared from compound (38) and propargylamine using the procedure described for compound (12). m.p. 121° C.
出典と根拠
- ORDレコード
- ord-708a03bd05a74f0e9e6a5bd0bf4064be
- 出典データセット
- uspto-grants-2004_12
- 特許番号
- US06831078B1
反応ノート
読み込み中…