1-Aminotetralin, (S)- → N-[3-(methylsulfanyl)benzyl]-N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amine

反応式

[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O.[C@@H:11]1([NH2:21])[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13][CH2:12]1>>[CH3:1][S:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH2:6][NH:21][C@@H:11]1[C:20]2[C:15](=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH2:14][CH2:13][CH2:12]1

参加物

反応物 2

HCID 70580741-Aminotetralin, (S)-

HCID 127211713-(Methylsulfanyl)benzaldehyde

生成物 1

HCID 69721790N-[3-(methylsulfanyl)benzyl]-N-[(1S)-1,2,3,4-tetrahydro-1-naphthalenyl]amine

実験手順

The product from Example 74A and (1S)-1,2,3,4-tetrahydro-1-naphthalenylamine were processed as described in Example 1A to provide the title compound.

出典と根拠

ORDレコード: ord-19c50976abdd40b881af768e70a76366
出典データセット: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06831193B2

反応ノート

読み込み中…