Acetic Anhydride → HCID 85612101、化合物

反応式

[OH:1][C:2]1[CH:3]=[C:4]([C:14]([OH:16])=[O:15])[C:5]([C:11]([OH:13])=O)=[CH:6][C:7]=1[C:8]([OH:10])=[O:9].[C:17](OC(=O)C)(=[O:19])[CH3:18]>>[C:17]([O:1][C:2]1[C:7]([C:8]([OH:10])=[O:9])=[CH:6][C:5]2[C:11](=[O:13])[O:16][C:14](=[O:15])[C:4]=2[CH:3]=1)(=[O:19])[CH3:18]

参加物

反応物 2

HCID 7918Acetic Anhydride

HCID 28017655-Hydroxybenzene-1,2,4-tricarboxylic acid

生成物 1

HCID 85612101HCID 85612101、化合物収率 38%

実験手順

4-Hydroxy-benzene-1,2,5-tricarboxylic acid (4.1 g, 18.1 mmol), prepared according to J. Am. Chem. Soc. (1949) 71, 11, was treated with acetic anhydride (50 mL) and heated at reflux for 5 hours. The mixture was allowed to cool to room temperature and then concentrated under reduced pressure. The orange-pink residue was washed with diethyl ether (3×30 mL) and dried under reduced pressure at room temperature overnight to provide the title compound (1.71 g, 38%).

後処理

temperatureheated
temperatureat reflux for 5 hours
concentrationconcentrated under reduced pressure
washThe orange-pink residue was washed with diethyl ether (3×30 mL)
customdried under reduced pressure at room temperature overnight

出典と根拠

ORDレコード: ord-5c303af4991e4d21b6ccb61744dd24ca
出典データセット: uspto-grants-2004_12
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06831193B2

反応ノート

読み込み中…

参加物